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10.1038/s41467-019-09277-9 Summary Keywords amino acids (AAs), metabolism, cancer, mTORC (mammalian target of rapamycin kinase complex), epigenetic, tumor immunity, ferroptosis, tumor growth Citation Wei Z, Liu X, Cheng C, Yu W and Yi P (2021) Metabolism of Amino Acids in Cancer

Hu Y, Tian X, Zhao Y, Wang Z, Lin M, Sun R, et al

This depletion is tightly linked to the breakdown of immune homeostasis, intestinal barrier dysfunction, and uncontrolled systemic inflammation, underscoring Clostridium s potential as a core target for microbiota-based immunotherapy

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Free radicals then damage DNA, cellular membranes and enzymes